Table 5.

Patient and Hospital Factors Associated With Hydralazine‐Isosorbide Dinitrate Use in Overall Cohort

Variable	Adjusted OR (95% CI)	P Value
Age, per 10 years	0.92 (0.89 to 0.96)	<0.0001
Female	0.82 (0.77 to 0.87)	<0.0001
Race, African American vs white	2.24 (2.00 to 2.84)	<0.0001
Race, Hispanic vs white	1.24 (1.05 to 1.46)	0.009
Medical history
Diabetes	1.27 (1.17 to 1.37)	<0.0001
Hypertension	1.27 (1.13 to 1.44)	0.0001
ICD implantation	1.26 (1.15 to 1.39)	<0.0001
Prior heart failure	1.27 (1.16 to 1.38)	<0.0001
Anemia	1.35 (1.23 to 1.49)	<0.0001
Renal insufficiency	2.56 (2.33 to 2.82)	<0.0001
Chronic dialysis	0.66 (0.49 to 0.90)	0.008
Smoking	0.84 (0.78 to 0.92)	<0.0001
Systolic BP, per 10 mm Hg	1.14 (1.12 to 1.16)	<0.0001
Heart rate, per 10 beats/minute	0.92 (0.90 to 0.94)	<0.0001

Candidate variables in the model included demographics (age, sex, race), insurance status, medical history (atrial fibrillation or flutter, chronic obstructive pulmonary disease, diabetes, dyslipidemia, hypertension, peripheral vascular disease, stroke, implantable cardioverter defibrillator implantation, previous history of heart failure, anemia, pacemaker, dialysis, renal insufficiency, depression, ischemic etiology of heart failure, smoker), vital signs (systolic BP and heart rate), hospital characteristics (region, teaching status and number of beds). Only statistically significant factors are reported in the table. CI indicates confidence interval; ICD, implantable cardioverter‐defibrillator; BP, blood pressure.