Table 6.

Patient and Hospital Factors Associated With Hydralazine‐Isosorbide Dinitrate Use in Self‐Identified African American Patients Meeting Guideline Criteria

Variable	Adjusted OR (95% CI)	P Value
Age, per 10 years	0.89 (0.85 to 0.94)	<0.0001
Female vs male	0.77 (0.69 to 0.87)	<0.0001
Insurance, uninsured vs Medicare	0.80 (0.68 to 0.94)	0.0072
Medical history
COPD	1.18 (1.06 to 1.31)	0.0021
Diabetes	1.21 (1.07 to 1.37)	0.0021
Hypertension	1.31 (1.07 to 1.61)	0.0091
ICD implantation	1.36 (1.19 to 1.55)	<0.0001
Prior heart failure	1.40 (1.23 to 1.59)	<0.0001
Anemia	1.28 (1.07 to 1.52)	0.006
Chronic dialysis	0.60 (0.42 to 0.86)	0.0055
Renal insufficiency	2.31 (1.99 to 2.69)	<0.0001
Smoking	0.82 (0.72 to 0.94)	0.0036
Systolic BP, per 10 mm Hg	1.15 (1.12 to 1.18)	<0.0001
Heart rate, per 10 beats/minute	0.93 (0.91 to 0.95)	<0.0001

Candidate variables in the model included demographics (age, sex), insurance status, medical history (atrial fibrillation or flutter, chronic obstructive pulmonary disease, diabetes, dyslipidemia, hypertension, peripheral vascular disease, stroke, implantable cardioverter‐defibrillator implantation, history of heart failure, anemia, pacemaker, dialysis, renal insufficiency, depression, ischemic etiology of heart failure, smoker), vital signs (systolic BP and heart rate), hospital characteristics (region, teaching status, and number of beds). Only statistically significant factors are reported in the table. CI indicates confidence interval; COPD, chronic obstructive pulmonary disease; ICD, implantable cardioverter‐defibrillator; BP, blood pressure.