Table 3.

Red Blood Cell Fatty Acid Concentrations Preintervention and Postintervention

	Control						DHA Supplemented						Comparison of Randomized Groups (P Value)
	All		Male		Female		All		Male		Female		All	Male	Female
N*
Preintervention	156		65		91		160		54		106
Postintervention	135		56		79		131		50		81
Docosohexenoic acid,† %
Preintervention	5.3	1.7	5.2	1.8	5.3	1.6	5.5	1.7	5.3	1.8	5.6	1.6	0.3	0.8	0.3
Postintervention	5.3	1.8	5.1	1.8	5.4	1.7	8.9	2.6	8.8	2.7	8.9	2.5	<0.0001	<0.0001	<0.0001
Eicosapentenoic acid,† %
Preintervention	1.0	0.6	1.1	0.6	0.9	0.5	1.0	0.5	1.0	0.6	1.0	0.5	0.7	0.5	0.2
Postintervention	0.9	0.5	1.0	0.5	0.9	0.5	1.3	0.6	1.2	0.6	1.4	0.6	<0.0001	0.01	<0.0001
Omega‐3 index†
Preintervention	6.2	2.1	6.2	2.3	6.3	2.0	6.5	2.1	6.3	2.3	6.6	2.0	0.3	0.9	0.2
Postintervention	6.2	2.2	6.1	2.2	6.3	2.2	10.2	3.0	10.0	3.1	10.3	2.9	<0.0001	<0.0001	<0.0001
Omega 3 index ≥8%, ‡%, n
Preintervention	19	30	17	11	21	19	22	35	22	12	22	23	0.3	0.3	0.5
Postintervention	16	22	16	9	16	13	76	100	70	35	80	65	<0.0001	<0.0001	<0.0001

DHA indicates docosahexaenoic acid; omega‐3 index, docosahexenoic+eicosapentenoic/total fatty acids.

^*Red cell fatty acids concentrations were successfully obtained in 98% (316/324) of participants at randomization and 97% (266/274) postintervention.

^†Data are mean, SD % of total fatty acids except ^‡percent and number of individuals.