Fig. 2.

Serum cytokines and chemokines. Sera from patients with early inflammatory arthritis (EIA), rheumatoid arthritis (RA) and healthy controls (HC) were frozen at −80°C until thawed for analysis using a multiplex assay. Cytokines and chemokines with significant differences versus HC are shown. Symbols represent individual patients and lines median values. Between-group comparisons were performed using the Kruskal–Wallis test with Dunn's post-test (versus healthy controls). Within the EIA group, patients classified as RA are shown by open symbols, and undifferentiated arthritis (UA) by closed symbols. *P < 0·05; **P < 0·01.