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. 2008 Dec 16;13(8a):1577–1585. doi: 10.1111/j.1582-4934.2008.00613.x

Fig. 2.

Fig. 2

MiR-126 is functionally active in vitro and can be specifically repressed by antagomir-126 in vitro and in vivo. (A) Relative firefly luciferase expression of HEK-293T and EC-RF24 transfected with a luciferase reporter plasmid harbouring 0 (pMIR), 1 (pMIR-126 M) or 4 (pMIR-126Q) perfect match target sites for miR-126 in the 3’UTR of the luciferase transcript (**=P< 0.01). (B) Relative firefly luciferase expression of transfected EC-RF24 incubated for 16 hrs with 5 μg/ml scram-blemir or antagomir-126 (*=P< 0.05 and **=P< 0.01).