Table 3.

Volume fraction (%) of tissue components in porous biphasic hydroxyapatite (HA)/β tricalcium phosphate (β-TCP) implanted in 16 calvarial defects of 4 adult baboons and harvested 90 and 365 days after implantation

Time	Biomimetic Matrices HA/β-TCP	Bone	Matrix	FVA
90	19/81 HA/β-TCP	37.7 ±3.9	28.5 ± 1.3	33.8 ±0.8
	4/96 HA/β-TCP	39.7 ±3.5	21.6 ±1.3	38.7 ±2.5
365	19/81 HA/β-TCP	53.7 ±3.4	26.6 ± 2.4	19.7 ±2.7
	4/96 HA/β-TCP	73.7 ± 3.5*	6.9 ±3.0*	19.4 ±2.3

Volume fractions (%) of tissue components in orthotopic calvarial specimens were calculated with a calibrated Zeiss Integration Platte II with 100 lattice points superimposed over five sources selected for histomorphometry in each section as described in ‘Materials and methods’. Values are given as means ± SEM of 4 specimens per treatment modality representing two animals per observation period. *P< 0.05 versus19/81 on day 90 and 365.