Table 1.
α-Glucosidase inhibitory activities and IC50 values of the studied Korean plant extracts
| Sr. No. | Plant name | Family | Plant part |
α
-glucosidase inhibition
|
|
|---|---|---|---|---|---|
| % Inhibition | IC 50 Values (µg/mL) a | ||||
| 1 | Actinidia arguta | Actinidiaceae | Whole plant | 33 ± 1 | -- |
| 2 | Meliosma oldhamii | Sabiaceae | Whole plant | 67 ± 3 | 150 ± 3 |
| 3 | Aster tataricus | Asteraceae | Stem | n. a. | -- |
| 4 | Capsella bursa-pastoris | Brassicaceae | Whole plant | 23 ± 1 | -- |
| 5 | Allium macrostemon | Alliaceae | Whole plant | 19 ± 2 | -- |
| 6 | Rhododendron schlippenbachii | Ericaceae | Leaf | 98 ±1 | 20 ± 1 |
| 7 | Pyrola japonica | Pyrolaceae | Whole plant | 29 ± 2 | -- |
| 8 | Symplocos chinensis | Symplocaceae | Leaf | 52 ± 2 | 220 ± 5 |
| 9 | Juglans regia | Juglandaceae | Whole plant | 99 ± 1 | 80 ± 2 |
| 10 | Sinapsis alba | Brassicaceae | Seed | 22 ± 2 | -- |
| 11 | Aster tataricus | Asteraceae | Root | 17 ± 3 | -- |
| 12 | Magnolia kobus | Magnoliaceae | Whole plant | 4 ± 1 | -- |
| 13 | Inula helenium | Asteraceae | Whole plant | 9 ± 2 | -- |
| 14 | Digitaria violascens | Poaceae | Whole plant | n. a. | -- |
| 15 | Dendropanax morbifera | Araliaceae | Whole plant | 39 ± 3 | -- |
| 16 | Sesamum indicum | Pedaliaceae | Whole plant | 11 ± 2 | -- |
| 17 | Alisma canaliculatum | Alismataceae | Rhizomes | 22 ± 3 | -- |
| 18 | Celtis sinensis | Cannabaceae | Whole plant | 25 ± 1 | -- |
| 19 | Astilbe chinensis | Saxifragaceae | Rhizomes | 95 ± 2 | 30 ± 2 |
| 20 | Corydalis remota | Papaveraceae | Whole plant | 23 ± 2 | -- |
| 21 | Phlomis umbrosa | Labiatae | Whole plant | 12 ± 2 | -- |
| 22 | Curcuma zedoaria | Zingiberaceae | Whole plant | 27 ± 2 | -- |
| 23 | Gleditsia japonica | Fabaceae | Whole plant | n. a. | -- |
| 24 | Miscanthus sinensis | Poaceae | Whole plant | 30 ± 3 | -- |
| 25 | Heracleum moellendorffii | Apiaceae | Whole plant | 17 ± 2 | -- |
| 26 | Draba nemorosa | Brassicaceae | Whole plant | 11 ± 1 | -- |
| 27 | Vaccinium hirtum | Ericaceae | Whole plant | 46 ± 1 | -- |
| 28 | Smilax sieboldii | Smilacaceae | Whole plant | 24 ± 3 | -- |
| 29 | Euonymus sachalinensis | Celastraceae | Leaf | 99 ± 1 | 10 ± 1 |
| 30 | Sinomenium acutum | Menispermaceae | Bark | 28 ± 2 | -- |
Note: The IC50 values of 1,2,3,4,6-penta-O-galloyl-β-D-glucose (positive control) for α-glucosidase inhibitory activity was measured as 0.37 ± 0.03 µg/mL, respectively.
a All results are represented as mean ± SD (n = 3).
n. a.: no activity. --: Not determined (IC50 values were only determined for the plant extracts with ≥ 50% inhibition at 5 mg/mL).