Table 1.
Groups (n = 6) |
Carageenan induced rat paw edema volume in mL (Mean ± SEM) (% inhibition)
|
||||
---|---|---|---|---|---|
0 (min) | 60 (min) | 120 (min) | 180 (min) | 240 (min) | |
Control, 0.1(mL), 1% Carageenan | 1.16 ± 0.005 | 1.64 ± 0.017 | 1.94 ± 0.009 | 2.30 ± 0.011 | 2.52 ± 0.01 |
Diclofenac sodium, 5 (mg/Kg) |
1.14 ± 0.006 | 1.18 ± 0.005* (28.04) |
1.25 ± 0.009** (35.56 ) |
1.34 ± 0.010** (41.73 ) |
1.44 ± 0.019** (42.85 ) |
DFA, 100 (mg/Kg) |
1.15 ± 0.008 | 1.53 ± 0.010 (6.70 ) |
1.70 ± 0.008** ( 12.37) |
1.81 ± 0.010** ( 21.30) |
2.05 ± 0.15** (18..56 ) |
DFA, 200 (mg/Kg) |
1.19 ± 0.005 | 1.46 ± 0.015* (10..97 ) |
1.54 ± 0.012** ( 20.61) |
1.64 ± 0.016** (28.69 ) |
1.85 ± 0.13** ( 26.58) |
DFA, 300 (mg/Kg) |
1.13 ± 0.005 | 1.30 ± 0.007* (20.73 ) |
1.42 ± 0.011** (26.80 ) |
1.54 ± 0.012** (33.04 ) |
1.74 ± 0.009** ( 30.95) |
DFM, 100 (mg/Kg) |
1.20 ± 0.012 | 1.55 ± 0.011** (5.48 ) |
1.80 ± 0.015** ( 7.21) |
2.04 ± 0.009** (11.30 ) |
2.30 ± 0.008** (8.73 ) |
DFM, 200 (mg/Kg) |
1.18 ± 0.005 | 1.51 ± 0.16 (7.92 ) |
1.77 ± 0.007** (8.76 ) |
1.96 ± 0.008** ( 14.78) |
2.22 ± 0.008** (11..90 ) |
DFM, 300 (mg/Kg) |
1.18 ± 0.005 | 1.48 ± 0.015* (9.75 ) |
1.65 ± 0.012** (14.94 ) |
1.85 ± 0.012** ( 19.56) |
1.93 ± 0.007** ( 23.41) |
DFA: Aqueous extract of Dendrophthoe Falcata leaves
DFM: Methanolic extract of Dendrophthoe Ffalcate leaves
* *: p< 0.01 *: p< 0.05 Values are expressed as Mean ± SEM, one-way analysis of variance followed by Dunnette’s multiple comparison -tests.