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The amino acid sequences of the N-termini of human, mouse, yeast and E. coli GR were aligned using ClustalW. Identical residues are highlighted in black, and similar residues are outlined in gray. For the eukaryotic sequences, the two methionines encoded by the two in-frame start codons are shown in bold. The predicted cleavage site for the MTS in yeast Glr1p is designated by an arrow (↑).
