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Morphological changes and fat accumulation in 3T3-L1 cells after 8 days of differentiation. During differentiation, cells were untreated (A), treated with 5 mM DFMO alone (B) or in combination with 100 μM (S)-MeSpd (C), (R)-MeSpd (D), (S,S)-Me2Spm (E) or (R,R)-Me2Spm (F). The cells were stained with Oil Red O on the differentiation day 8. Scale bar, 200 nm.
