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The coiled coil domain of CagF interacts with domains II-III of CagA. Isothermal titration calorimetry binding curves of the CagA1–885-CagFL36A (A), CagA1–885-CagFI39A (B), CagA1055–1247-CagFL36A (C), CagA1055–1247-CagFI39A (D), and CagA256–885-CagFI39A (E) interactions are shown.
