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Time course of neutrophil enzyme-activated MAPK signaling in KNRK-PAR1-eYFP cells. Activation of p42/44 MAP kinse by: A, thrombin (Thr); B, TFLLR-NH2 (TF); C, NE; and D, PR3 in KNRK-PAR1-eYFP cells. E, graph showing densitometry analysis of normalized p42/44 MAP kinase activation in KNRK-PAR1-eYFP cells over 90 min. Data are expressed as mean ± S.E., n = 3.
