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. 2013 Oct 7;288(46):33193–33204. doi: 10.1074/jbc.M113.496133

FIGURE 4.

FIGURE 4.

Rescue by unassisted Top3 requires factors that enable the accumulation of unresolved recombination intermediates within sgs1Δ mutants. A, sgs1Δ cells lacking additional factors that render them unable to accumulate recombination intermediates, with or without endogenous TOP3, were spotted onto YPAD containing the indicated concentrations of MMS. B, identical to A except comparing the effects of TOP3 overexpression.