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. 2013 Sep 26;288(46):33398–33410. doi: 10.1074/jbc.M113.499848

TABLE 2.

Comparison of actin binding behavior among different paralogs

For each NM II, the percentage of filaments bound to actin or unbound is shown. Bound filaments were classified as type 1 (bound to a single actin filament via one side of the myosin filament; e.g., Fig. 8, A–D), type 2 (bound to a single actin filament by both sides of the myosin filament; e.g., Fig. 8G), type 3 (bound to multiple actin filaments by one side of the myosin filament; e.g., Fig. 8E), or type 4 (bound to multiple actin filaments by both sides of the myosin filament; e.g., Fig. 8F). Each type is quantified as a percentage of all filaments, and types 2, 3, and 4 are not mutually exclusive.

Paralog Bound Unbound Type 1 Type 2 Type 3 Type 4
% % % % % %
NM IIA 72 28 15 15 40 43
NM IIB 89 11 14 24 66 68
NM IIB2 64 36 37 6 14 16
NM IIC 47 53 30 3 7 11