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. 2013 Sep 17;2:190. [Version 1] doi: 10.12688/f1000research.2-190.v1

Table 1. Regions of missing electron density in human proteins involved in the p53-mediated apoptotic pathways.

Protein name PDB ID Regions of missing electron density
TRAIL 1DG6 91–119, 131–141, 195–196
Fibroblast growth factor receptor 2 1DJS
1GJO
297–306
453–466, 504–506, 581–595, 766–768
FAS 3THM 1–35, 92–93, 122–164
PI3K (regulatory subunit) 2XS6 85–108, 202–203, 257–274, 295–298
PI3K (catalytic subunit) 2RD0 1–7, 307–324, 415–423, 506–527, 941–950, 1051–1068
PTEN 1D5R 7–13, 282–285, 309–312, 352–353
AKT 3O96 46–48, 89–91, 114–144, 189–198, 299–312, 430–443
Caspase-3 1CP3 1–34, 174–184
Caspase-6 2WDP 1–30, 166–199, 262–266
Caspase-9 1JXQ 139–147, 296–297, 404–409
Chk2 3I6W 70–91, 228–232, 254–267, 370–401, 502–512
Chk1 1IA8 1, 46–47, 277–289
BCL2 1GM5 1–2
APAF-1 1Z6T 95–104, 587–591