Table 1. Regions of missing electron density in human proteins involved in the p53-mediated apoptotic pathways.
Protein name | PDB ID | Regions of missing electron density |
---|---|---|
TRAIL | 1DG6 | 91–119, 131–141, 195–196 |
Fibroblast growth factor receptor 2 | 1DJS
1GJO |
297–306
453–466, 504–506, 581–595, 766–768 |
FAS | 3THM | 1–35, 92–93, 122–164 |
PI3K (regulatory subunit) | 2XS6 | 85–108, 202–203, 257–274, 295–298 |
PI3K (catalytic subunit) | 2RD0 | 1–7, 307–324, 415–423, 506–527, 941–950, 1051–1068 |
PTEN | 1D5R | 7–13, 282–285, 309–312, 352–353 |
AKT | 3O96 | 46–48, 89–91, 114–144, 189–198, 299–312, 430–443 |
Caspase-3 | 1CP3 | 1–34, 174–184 |
Caspase-6 | 2WDP | 1–30, 166–199, 262–266 |
Caspase-9 | 1JXQ | 139–147, 296–297, 404–409 |
Chk2 | 3I6W | 70–91, 228–232, 254–267, 370–401, 502–512 |
Chk1 | 1IA8 | 1, 46–47, 277–289 |
BCL2 | 1GM5 | 1–2 |
APAF-1 | 1Z6T | 95–104, 587–591 |