Table 5.
Associations of disease severity and age, disease duration, attack intervals, and number of presenting symptoms
| Total | Chronic | Mild-moderate | Advanced - Accelerated | Aggressive - Malignant | P | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||
| Mean ± SD | Median (Range) | Mean ± SD | Median (Range) | Mean ± SD | Median (Range) | Mean ± SD | Median (Range) | Mean ± SD | Median (Range) | ||
| Age (years) | 34.0 ± 10.0 | 33.0 (12-58) | 30.0 ± 8.0 | 30 (15-46) | 33.0 ± 10.0 | 32 (12-55) | 35.0 ± 10.0 | 34 (17-58) | 37.0 ± 10.0 | 37 (16-58) | < 0.001 |
| Disease duration (years) | 7.6 ± 5.6 | 6.0 (1-30) | 6.2 ± 3.5 | 5 (3-16) | 7.4 ± 6.2 | 5 (1-30) | 8.5 ± 5.4 | 8 (1-25) | 7.7 ± 5.2 | 6 (1-29) | 0.022 |
| Age at disease onset (years) | 26.4 ± 8.7 | 24.5(5-54) | 24.0 ± 6.9 | 23 (11-43) | 25.8 ± 8.8 | 24 (10-54) | 26.7 ± 8.5 | 24 (5-47) | 29.0 ± 9.4 | 27 (14-51) | < 0.001 |
| Number of symptoms | 2.0 ± 1.5 | 1.5(0-11) | 1.5 ± 0.9 | 1(0-4) | 1.9 ± 1.3 | 1 (0-8) | 2.2 ± 1.6 | 2 (0-8) | 2.6 ± 1.9 | 2 (1-11) | < 0.001 |
| Interval between the 1st and 2nd attacks (Months) | 26.0 ± 35.0 | 12.0 (0-204) | 30.0 ± 25.0 | 24 (3-132) | 34.0 ± 40.0 | 12(0-204) | 21.0 ± 33.0 | 12 (0-180) | 11.0 ± 20.0 | 3 (0-108) | < 0.001 |