FIGURE 5.

Regions affected by glycan binding. Chemical shifts with perturbations greater than 1 × S.D. upon the addition of 5 mm (GlcNAc)₂Man₃ (A), Man₃ (B), Man₅ (C), and Man₉GlcNAc (D) are shown in red mapped onto the structure of the (GlcNAc)₂Man₃·CDR complex (Protein Data Bank code 1K9J). A schematic of the bound glycan is given in the lower right corner of each panel. These maps highlight the conserved binding regions as well as regions unique to each glycan.