FIGURE 2.

Metal exposure and analysis of cell survival. Cell survival data compared WT and DJ-1^−/− MEF cells exposed to increasing concentrations of metals for 24 h. All values were compared with nontreated control set to 100% survival and plotted against the logarithmic scale for the used metal concentrations. A, CuCl, WT LC₅₀ = 70 μm, DJ-1^−/− LC₅₀ = 30 μm. B, HgCl₂, WT LC₅₀ = 15 μm, DJ-1^−/− LC₅₀ = 4 μm. Statistically significant change in cell survival compared with DJ-1^−/− cells is indicated with *, p < 0.05.