Table 1.

Brain Imaging Literature on Healthy Control Subjects using Visceral Stimuli (all studies used volume/pressure controlled distension)

Author	Year	Reference	Site	Imaging Modality	N tot	M	F	postIns	antIns	ACC	S1	PFC	POC	Tha	BA6	Cereb	PCC	MCC	M1	S2	PAG	TP	OFC	SM	NC
Hamaguchi	2004	109	Cdist	PET	15	15	0	B+	B+	L+		R+	B+	B+		B+					B+	L+	R+	R+	L+
Aziz Q	1997	23	E	PET	8	7	1	B+	B+	B+	B+				B+				B+
Binkofsky F	1998	21	E	fMRI	5	5	0		L+	B+	B+				R+					B+
Aziz Q	2000	24	Edist	fMRI	6	6	0	R+	R+	R+	B+	L+	B+		L+	L+		R+	R+	L+
Aziz Q	2000	24	Epost	fMRI	6	6	0	R+	R+		L+	R+			L+		R+	R+	L+
Strigo	2002	38	E	fMRI	7	4	3	L+	R+	L+	B+		B+	L+	B+	B+			B+	B+
Phillips ML	2003	48	E	fMRI	8	8	0	B+	B+	R+			B+			B+	B+					B+
Lawal	2008	110	Edist	fMRI	20	4	16	B+	B+								B+	B+
Paine	2008	111	Edist	fMRI	7	4	3	R+	R+		R+								R+
Ladabaum	2001	29	Gdist	PET	15	6	9	B+	B+	R+		B+		B+		B+					B+				B+
Stephan	2003	112	Gprox	PET	18	0	18		B+	R+													B+
Lu	2004	113	Gdist	fMRI	10	8	2			B+		B+		B+		B+	B+
Vandenbergh J	2005	114	Gpost	PET	11	5	6		R+	R+		R+			B+	L+		R+	B+			L+
Ladabaum	2007	115	Gprox	fMRI	18	8	10	B+	B+	L+		R+		B+		B+	B+		L+					R+
Wang	2007	116	Gprox	fMRI	18	15	3	B+	B+		L+								L+
Van Oudenhove	2008	117	Gpost	PET	11	5	6			B+	L+	R+				R+			B+						B+
Kern	1998	22	R	fMRI	10	4	6	B+	B+	B+		B+	B+				B+
Bouras	1999	118	R	SPECT	10	3	7			B+				B+
Hobday	2001	30	R	fMRI	8	8	0	B+	B+	B+	B+	B+			R+					B+			B+	B+
Lotze	2001	33	R	fMRI	8	4	4	B+	B+	B+	B+		B+		R+	L+		B+	L+	B+	B+		R+	B+
Verne	2002	119	R	fMRI	9	3	6	L+	L+		R+			R+			L+	L+
Dunkley	2005	43	R	fMRI	10	5	5	B+						B+							B+				B+
Lawal	2005	120	R	fMRI	18	8	10			B+							B+
Bittorf	2006	121	R	fMRI	13	11	2	B+	B+	B+				B+	B+					B+
Song	2006	122	R	fMRI	12	0	12		B+		B+	B+	B+	B+		L+				B+
Berman	2008	83	R	fMRI	12	0	12	B+	B+
Eickhoff	2008	123	R	fMRI	8	4	4		L+				L+	L+					L+
Kwan	2005	99	R	fMRI	11	na	na		R+	R+
Verne	2003	119	R	fMRI	9	3	6		R+	L+
Andresen	2005	124	R	fMRI	8	5	3	B+	B+		B+			B+						B+
Naliboff	2001	28	R	PET	12	10	2			B+		B+		B+		R+							B+

Legend: Abbreviations used

ACC Anterior cingulate cortex

BA Brodmann area

B−/B+ Bilateral deactivation/activation

Cereb Cerebellum

Cdist Distal colon distension

Edist Distal esophagus distension

Eprox Proximal esophagus distension

F Frontal area

fMRI Functional Magnetic Resonance Imaging

G Gastric Distention

antIns Anterior insular cortex

postIns Posterior insular cortex

L+/− Left activation/ deactivation

M Males

M1 Primary motor cortex

MCC Middle cingulate cortex

NC Nucleus caudatus

NA Number unknown

OFC Orbitofrontal cortex

PAG Periaqueductal grey

PET Positron emission tomography

PFC Prefrontal cortex

POC Parieto occipital cortex

R Rectal distension

R+/− Right activation/ deactivation

SM Supramarginal gyrus (BA39/40)

S1 Primary sensorial area

S2 Secondary sensorial area

SPECT Single positron emission tomography

Tha Thalamus

Tot total

UC Ulcerative colitis