TABLE 2.

Kinetic parameters of hGLUT2 mutants using 2-DOG

hGLUT2	Km	Vm
	mm of 2-DOG	nmol/min/oocyte
WT	22 ± 3	422 ± 20
SNP
P68L	24 ± 4	384 ± 20
T110I	20 ± 4	436 ± 30
Additional missense mutations
G20S	30 ± 6a	540 ± 45a
F295Y	17 ± 3b	300 ± 18
L368P	23 ± 4	215 ± 15a

^a p < 0.001.

^b p < 0.01 in comparsion with WT.