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. 2013 Oct 25;4:166. doi: 10.3389/fneur.2013.00166

Figure 2.

Figure 2

Secondary VBM group analysis. Secondary VBM analysis confirmed the finding of subgroups of MTLE-NL patients with or without amygdala enlargement detected by automatic volumetry. (A) VBM demonstrated bilateral increased amygdala gray matter volume in the enlarged amygdala group (N = 8); (B) VBM also detected increased amygdala gray matter volume in the subgroup of patients with borderline amygdala volumes (amygdala volumes z-score higher than 1.5 SD in the volumetric analysis; N = 14); (C) VBM analysis did not detected increase gray matter volumes in the subgroup of patients with normal amygdala defined by the volumetric analysis. VBM, Two-sample t-test, p < 0.05, FDR corrected, minimum cluster size of 30 voxels. MTLE-NL, mesial temporal lobe epilepsy with normal MRI; VBM, voxel-based morphometry; FDR, false discovery rate; T, T score.