TABLE 2.
Urine Arsenic Metabolite Patterns (% Species) by Genotype
| SNP | Genotype | Trait | Mean | SD | Minimum | Maximum | N |
|---|---|---|---|---|---|---|---|
| Overall | — | %iAs | 8.8 | 4.9 | 1.1 | 31.9 | 157 |
| — | %MMA | 14.7 | 5.2 | 5.1 | 30.7 | 157 | |
| — | %DMA | 76.4 | 8.6 | 31.3 | 91.5 | 157 | |
| rs1564370 | C/C | %iAs | 8.2 | 3.7 | 3.0 | 16.9 | 26 |
| C/G | %iAs | 8.2 | 4.6 | 1.1 | 23.9 | 68 | |
| G/G | %iAs | 9.8 | 5.6 | 1.1 | 38.0 | 63 | |
| C/C | %MMA | 13.9 | 5.2 | 7.4 | 25.4 | 26 | |
| C/G | %MMA | 13.5 | 4.5 | 5.1 | 29.5 | 68 | |
| G/G | %MMA | 16.4 | 5.4 | 8.1 | 30.7 | 63 | |
| C/C | %DMA | 77.9 | 7.7 | 61.8 | 89.5 | 26 | |
| C/G | %DMA | 78.3 | 7.2 | 60.7 | 91.5 | 68 | |
| G/G | %DMA | 73.8 | 9.7 | 31.3 | 87.6 | 63 | |
| rs2291075 | A/A | %iAs | 6.2 | 4.4 | 3.1 | 9.4 | 2 |
| A/G | %iAs | 7.4 | 3.6 | 2.2 | 16.9 | 24 | |
| G/G | %iAs | 9.2 | 5.1 | 1.1 | 38.0 | 131 | |
| A/A | %MMA | 8.6 | 1.6 | 7.4 | 9.8 | 2 | |
| A/G | %MMA | 12.3 | 3.8 | 5.6 | 21.2 | 24 | |
| G/G | %MMA | 15.2 | 5.2 | 5.1 | 30.7 | 131 | |
| A/A | %DMA | 85.2 | 6.1 | 80.9 | 89.5 | 2 | |
| A/G | %DMA | 80.3 | 5.8 | 66.2 | 88.6 | 24 | |
| G/G | %DMA | 75.6 | 8.8 | 31.3 | 91.5 | 131 | |
| rs2417955 | A/A | %iAs | 8.8 | 4.6 | 1.1 | 23.9 | 96 |
| A/T | %iAs | 9.3 | 5.6 | 1.8 | 38.0 | 56 | |
| T/T | %iAs | 5.9 | 2.3 | 3.1 | 9.4 | 5 | |
| A/A | %MMA | 15.1 | 4.9 | 5.8 | 30.3 | 96 | |
| A/T | %MMA | 14.6 | 5.5 | 5.1 | 30.7 | 56 | |
| T/T | %MMA | 9.1 | 2.0 | 7.4 | 12.2 | 5 | |
| A/A | %DMA | 76.2 | 7.8 | 54.8 | 91.5 | 96 | |
| A/T | %DMA | 76.1 | 9.8 | 31.3 | 88.6 | 56 | |
| T/T | %DMA | 85.1 | 3.9 | 80.9 | 89.5 | 5 | |
| rs2900478 | A/A | %iAs | 8.9 | 5.0 | 1.1 | 38.0 | 144 |
| A/T | %iAs | 7.5 | 4.2 | 2.2 | 16.9 | 12 | |
| A/A | %MMA | 15.0 | 5.2 | 5.1 | 30.7 | 144 | |
| A/T | %MMA | 12.2 | 3.5 | 7.9 | 17.2 | 12 | |
| A/A | %DMA | 76.1 | 8.7 | 31.3 | 91.5 | 144 | |
| A/T | %DMA | 80.3 | 6.8 | 66.2 | 87.6 | 12 | |
| rs4149063 | A/A | %iAs | 11.1 | 1.7 | 9.3 | 12.9 | 4 |
| A/C | %iAs | 9.7 | 4.7 | 1.9 | 23.9 | 56 | |
| C/C | %iAs | 8.2 | 5.1 | 1.1 | 38.0 | 97 | |
| A/A | %MMA | 17.8 | 6.3 | 10.0 | 25.4 | 4 | |
| A/C | %MMA | 15.0 | 4.7 | 6.7 | 29.5 | 56 | |
| C/C | %MMA | 14.4 | 5.4 | 5.1 | 30.7 | 97 | |
| A/A | %DMA | 71.1 | 7.8 | 61.8 | 80.7 | 4 | |
| A/C | %DMA | 75.3 | 7.4 | 60.7 | 88.3 | 56 | |
| C/C | %DMA | 77.3 | 9.1 | 31.3 | 91.5 | 97 |