FIG. 2.

Airborne PCB-induced perturbations in RWPE-1 cell growth and decreased level of clonogenic survival. Asynchronously growing cultures of RWPE-1 cells were given fresh complete media daily containing 3μM PCBs for 5 days. Monolayer cultures were trypsinized, and cell numbers counted from day 1 to day 5 (Panel A). Each data point represents mean ± 1 SD of n = 6 treatment dishes from 2 separate experiments. *p < .001 compared with control. Panel B shows the data from the cells that were plated for clonogenic cell survival. Error bars represent mean ± 1 SD of n = 4 treatment dishes done in 2 separate experiments where each treatment dish was used to prepare 3 replicate cloning dishes for analysis. *p < .001 compared with control day 3, ^† p < .001 compared with control day 4, ^¶ p < .001 compared with control day 5. Abbreviation: PCB, polychlorinated biphenyl.