Figure 1.

VEGF-A concentrations in the media of no-grow (NG) (n = 27), slow-grow (SG) (n = 49) and fast-grow (FG) (n = 15) follicles (from 6 monkeys) as a function of weeks in culture in the presence of 5% O₂ and high/mid FSH levels. Data are presented as non-transformed—mean ± SEM. ^a,b,cSignificant differences between Weeks 2, 3, 4 and 5 for NG (blue), SG (red) and FG (black) follicles, respectively (P < 0.05). *^,†,#Significant differences between NG, SG and FG follicles at Weeks 4 and 5 (P < 0.05). Growing follicles reached the antral stage (arrow) at 3–4 weeks of culture (Xu et al., 2011).