Table 3.
Survival statistics by period of diagnosis
| Kaplan–Meier Survival Statistics |
||||
|---|---|---|---|---|
| Deaths/Cases | 1-y, % (95% CI) | 2-y, % (95% CI) | Median, mo (interquartile range) | |
| Full cohort | ||||
| All years (1997–2008) | 1618/1645 | 25.3 (23.2–27.4) | 7.3 (6.1–8.6) | 5.8 (2.6–12.1) |
| Period of diagnosis | ||||
| 1997–2000 | 516/518 | 24.3 (20.7–28.1) | 5.2 (3.5–7.4) | 5.5 (2.6–11.8) |
| 2001–2004 | 582/586 | 22.4 (19.1–25.8) | 6.5 (4.7–8.7) | 5.7 (2.5–11.7) |
| 2005–2008 | 520/541 | 29.4 (25.6–33.3) | 10.2 (7.8–13.0) | 6.4 (2.8–13.2) |
| Log-rank test Pa | .0039 | |||
| Stratified log-rank test Pb | <.0001 | |||
| Restricted cohort (treated with resection and radiotherapy) | ||||
| All years (1997–2008) | 910/932 | 37.5 (34.3–40.5) | 11.2 (9.3–13.4) | 9.4 (5.3–14.9) |
| Period of diagnosis | ||||
| 1997–2000 | 303/305 | 33.8 (28.5–39.1) | 7.9 (5.2–11.2) | 8.3 (4.7–13.6) |
| 2001–2004 | 324/327 | 34.3 (29.2–39.4) | 10.7 (7.6–14.3) | 9.2 (5.3–14.6) |
| 2005–2008 | 283/300 | 44.7 (39.0–50.2) | 15.3 (11.4–19.6) | 10.6 (6.1–16.9) |
| Log-rank test Pa | .0001 | |||
| Stratified log-rank test Pb | <.0001 | |||
aCompares the Kaplan–Meier survival proportions across the 3 periods of diagnosis.
bCompares the Kaplan–Meier survival proportions across the 3 periods of diagnosis, controlling for age at diagnosis (≤39 y, 40–44, 45–49, … 80–84, 85+) and baseline Charlson comorbidity score (0, ≥1, unknown).