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. 2013 Oct 24;15(12):1625–1634. doi: 10.1093/neuonc/not124

Fig. 5.

Fig. 5.

Biomarker gene expressions in GBM subtypes. (A) Fibulin-1 (FBLN1), (B) SLIT3, (C) LINGO1, (D) spondin1 (SPON1), and (E) Plexin-B2 (PLXNB2) expression for mesenchymal (Mes) (left bar) or proneural (PN) (right bar) GBM subtypes obtained from TCGA—either (i) Affymetrix or (ii) Agilent, (iii) Rembrandt, or (iv) Erasmus databases. Increased fibulin-1 (A), SLIT3 (B), and Plexin-B2 (E) expressions are associated with mesenchymal phenotype in GBM (compared with the proneural subtype), whereas increased LINGO1 (C) and spondin1 (D) expressions are associated with the proneural subtype. P-values for each marker are shown for each database. For statistical analysis, a Welch's 2-sample t-test was used.