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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Neurobiol Aging. 2013 Aug 17;35(1):10.1016/j.neurobiolaging.2013.07.013. doi: 10.1016/j.neurobiolaging.2013.07.013

Figure 2.

Figure 2

A) Individual and combined effects of SNCA rs356219, SNCA rs11931074, and LRRK2 p.R1398H on risk of PD in the Asian series. SNCA rs356219 and rs11931074 were considered under a recessive model (i.e. presence vs. absence of two copies of the minor allele). For SNCA rs356219, the risk genotype was GG. For SNCA rs11931074, the risk genotype was TT; B) Individual and combined effects of SNCA rs356219, SNCA rs11931074, and LRRK2 p.R1398H on risk of PD in the Asian series. SNCA rs356219 and rs11931074 were considered under a dominant model (i.e. presence vs. absence of the minor allele). For SNCA rs356219, the risk genotype was AG or GG. For SNCA rs11931074, the risk genotype was GT or TT. Figures 2A–2B) For LRRK2 p.R1398H, the protective genotype was GA or AA (i.e. presence of the minor allele); NA indicates that a given SNP was not involved in the particular portion of the analysis.