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. 2013 Aug 29;113(11):8546–8566. doi: 10.1021/cr400046x

Figure 4.

Figure 4

Simplified outline of a multisubunit RNAP elongation mechanism indicating potential rate-determining steps. Estimated or determined rate constants for elemental steps can be found in the text and references. EDTA-r/s: EDTA-resistant or -sensitive intermediates.