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Cumulative released dose of BMP-2. In the first three days, the released dose of BMP-2 was relatively large and the gradient of the curve was steep. The rate of BMP-2 release decreased from 13 days onwards and the gradient of the curve became gradually less steep. The total released dose increased steadily after 10 days. BMP-2, bone morphogenetic protein-2; MBG, mesoporous bioactive glass.
