Table I.
Weight, ABG and W/D ratio of experiment rats.
| Groups | n | Weight (g) | pH | Pressure of O2 (mmHg) | Pressure of CO2 (mmHg) | W/D ratio | Histopathological score |
|---|---|---|---|---|---|---|---|
| Sham | 6 | 257.97±8.01 | 7.41±0.09 | 153.50±23.87 | 37.50±4.18 | 5.71±0.41 | 2.39±0.83 |
| IR | 6 | 260.53±6.0 | 7.40±0.07 | 146.17±18.45 | 35.67±5.43 | 7.28±0.50b | 4.61±0.39b |
| LDH | 6 | 258.02±9.78 | 7.43±0.09 | 141.17±29.03 | 35.50±4.64 | 6.13±0.82c | 4.00±0.70b |
| HDH | 6 | 259.93±9.91 | 7.38±0.07 | 156.50±34.80 | 35.33±5.05 | 5.84±0.53d | 3.61±0.25a,c |
| Y+D | 6 | 262.38±5.28 | 7.40±0.07 | 130.33±13.87 | 36.50±3.89 | 6.46±0.62a,c | 4.12±0.59b |
| Y | 6 | 262.10±7.76 | 7.37±0.04 | 137.50±20.01 | 37.50±5.05 | 7.20±0.76b | 4.28±0.49b |
Data presented are the mean ± SD. aP <0.05 and bP<0.01, vs. the sham group; cP <0.05 and dP<0.01, vs. the IR group. ABG, arterial blood gas; W/D ratio, wet/dry weight ratio of lung; IR, ischemia-reperfusion; LDH, low dose dexmedetomidine hydrochloride; HDH, high dose dexmedetomidine hydrochloride; Y+D, yohimbine and dexmedetomidine hydrochloride; Y, yohimbine.