Protective effects of bone marrow-derived mesenchymal stem cells (BM-MSCs) on renal function in rats with acute kidney injury (AKI). Rats were divided into three groups: the control group (con, n=8), cisplatin-treated rats administered saline (cis, n=8) and cisplatin-treated rats administered BM-MSCs (cis + msc, n=8). Renal function was assessed by measuring blood urea nitrogen (BUN), serum creatinine, urinary creatinine and urinary microalbumin levels. Data are presented as the means ± SEM. (A) Serum levels of BUN; con vs. cis, **P<0.01 between the indicated groups; cis vs. cis + msc, **P<0.01 between the indicated groups. (B) Serum levels of creatinine; con vs. cis, **P<0.01 between the indicated groups; cis vs. cis + msc, **P<0.01 between the indicated groups. (C) Urine levels of creatinine; con vs. cis, *P<0.05 between the indicated groups; cis vs. cis + msc, **P<0.01 between the indicated groups. (D) Urine levels of microalbumin; con vs. cis, **P<0.01 between the indicated groups; cis vs. cis + msc, **P<0.01 between the indicated groups.