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SEM images of osteoblast-like cells (SaOS-2) cells cultured on collagen (Col) composites for 1 and 4 weeks. At 1 week, the cells well adhered to and spread on the surfaces of Col, while extending the cellular process. At 4 weeks, the cells covered the surfaces of Col, occupying an area similar to that at 1 week, while losing the cellular process. Round particulates co-existed. The cells cultured on Col were fibroblastic for up to 4 weeks. W, week.
