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Comparison between the experimental plasma concentration value [ 5 ] and the model curves in the case of intravenous constant-rate infusion with an infusion time of 20 minutes. a 1 ) plasma concentration after a dose of 1 μg·kg −1 ·min −1 ; a 2 ) plasma concentration after a dose of 4 μg·kg −1 ·min −1 ; a 3 ) plasma concentration after a dose of 8 μg·kg −1 ·min −1 .
