TABLE I .

Values and dimensions of the three-compartmental model parameters.

Parameter	Optimized value	Parameter	Optimized value
V 1	7.88 mL	k 10	0.172 min −1
V 2	23.9 mL	k 12	0.373 min −1
V 3	13.8 mL	k 21	0.103 min −1
C l1	2.08 mL·min −1	k 13	0.0367 min −1
C l2	0.828 mL·min −1	k 31	0.0124 min −1
C l3	0.0784 mL·min −1