Table 1.
Baseline characteristics of the statins and non-statin therapy groups
| Statin (n =123) | Non-Statin (n = 675) | P -value | PS Adjusted P-Value | |
|---|---|---|---|---|
| Age, mean ± SD, years |
67.1 ± 11.3 |
47.1 ± 21.1 |
<0.001 |
0.59 |
| APACHE II, mean ± SD |
26.7 ± 8.1 |
23.5 ± 9.1 |
0.0002 |
0.90 |
| GCS, mean ± SD, |
9.0 ± 4.6 |
8.5 ± 4.0 |
0.20 |
0.96 |
| Creatinine, mean ± SD, μmol/L* |
228.0 ± 179.3 |
146.4 ± 133.8 |
<0.001 |
0.81 |
| INR, mean ± SD |
1.3 ± 0.5 |
1.4 ± 0.7 |
0.03 |
0.93 |
| aPTT, mean ± SD, |
43.4 ± 57.1 |
42.2 ± 60.8 |
0.83 |
1.00 |
| Trauma, No% |
3 (2.4) |
223 (33.0) |
<0.001 |
0.007 |
| Femur fracture, No.% |
2 (1.6) |
50 (7.4) |
0.02 |
0.45 |
| Any central line present, No. (%) |
91(74.0) |
504 (74.7) |
0.87 |
0.78 |
| Bedridden for > 3 days, No. (%) |
84 (68.3) |
310 (45.9) |
<0.001 |
0.44 |
| Malignancy, No. (%) |
8 (6.5) |
86 (12.7) |
0.05 |
0.77 |
| Recent surgery, No. (%) |
22 (17.9) |
221(32.7) |
0.001 |
0.65 |
| Previous VTE, No. (%) |
4 (3.3) |
8 (1.2) |
0.08 |
0.98 |
| Hemodialysis catheter, No. (%) |
33 (26.8) |
125 (18.5) |
0.03 |
0.71 |
| Compression stocking, No. (%) |
26 (21.1) |
172 (25.5) |
0.31 |
0.79 |
| Sequential compression device, No. (%) |
29 (23.6) |
227 (33.6) |
0.03 |
0.75 |
| Unfractionated heparin, No. (%) |
97 (78.9) |
405 (60.0) |
<0.001 |
0.58 |
| Enoxaparin, No. (%) |
16 (13.0) |
212 (31.4) |
<0.001 |
0.21 |
| Platelet transfusion, No. (%) | 12 (9.8) | 132 (19.6) | 0.009 | 0.97 |
P-values are provided for the differences between the two groups significant before and after propensity score adjustment.
APACHE: Acute physiology and chronic health evaluation, GCS: Glasgow coma scale, INR: International normalized ratio.
aPTT: activated partial thromboplastin time, VTE: Venous thromboembolism, PS: propensity score.
*To convert to conventional units in mg/dL, divide by 88.4.