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. 2013 Nov 15;8(11):e80338. doi: 10.1371/journal.pone.0080338

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© 2013 Zhou et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Low expression of Beclin 1 was closely correlated with poor overall survival and (B) progression-free survival in the testing set (n = 111). (C) Patients with lower Beclin 1 expression also acquired an inferior overall survival and (D) progression-free survival in the the overall patient cohort (n = 216). In the testing set and the overall patient cohort, the median duration of overall survival for patients with high and low expression of Beclin 1 was 108 VS. 24.5 months (p < 0.001) and 108 VS.28 months (p < 0.001), respectively.