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. 2013 Nov 15;8(11):e80474. doi: 10.1371/journal.pone.0080474

Table 1. Kinase inhibition parameters.[a] .

IC50 (μM) H
Imatinib 50 µM ATP 0.040±0.004 0.71±0.05
500 µM ATP 0.409±0.040 0.71±0.05
Abltide 50 µM ATP 21.51±2.64 0.89±0.10
500 µM ATP 37.47±3.95 1.80±0.31
[a]

Inhibitory concentration (IC50) and Hill slope (H) determined by fitting dose-response plots with a sigmoidal curve (see Figure 5).