Table 1. Biomarker concentrations in cerebrospinal fluid and plasma.4 .
| Marker | Boxer Test A1 | Boxer Test B2 | Controls | P-value | ||
| N = 30 | N = 26 | N = 254 | A vs C | A vs B | B vs C | |
| Md(range)SD ng/L | Md(range)SD ng/L | Md(range)SD ng/L | ||||
| pNFH 3 | 163(49–562)117 | 68(23–1503)298 | 33 (27–1265) 251 | 0.000 | 0.018 | 0.018 |
| AβN38 | 1541(715–2890)606 | 1538(566–2733)578 | 1578 (925–3066) 582 | 0.618 | 0.622 | 0.851 |
| AβN40 | 7211(4017–11100)1919 | 7290(3315–10979)1836 | 7588(4887–10610)1658 | 0.993 | 0.501 | 0.638 |
| AβN42 | 589(276–1380)268 | 606(227–1002)216 | 641(378–1119)214 | 0.846 | 0.657 | 0.468 |
| Aβ 1-42 4 | 12(4–27)5 | 12(0.0–20)4 | 12(0.7–19) 4 | 0.906 | 0.288 | 0.861 |
| sAPPα | 635(319–1122)189 | 666(227–1048)209 | 587 (359–988) 180 | 0.654 | 0.218 | 0.442 |
| sAPPβ | 207(110–405)80 | 220(54–508)97 | 197(116–406) 78 | 0.565 | 0.334 | 0.462 |
| ApoE | 4597(2659–9577)1647 | 4411(2751–7859)1321 | 3977(2131–7192)1432 | 0.128 | 0.534 | 0.109 |
| ApoA1 | 1936(834–4673)1018 | 2435(1273–5589)986 | 2155(1033–5853)1247 | 0.710 | 0.006 | 0.221 |
1
Test A: 1–6 days after last bout;
2
Test B: No boxing for at least 14 days.
3
According to pNFH, the result from one of the controls was destroyed.
4
Aβ 1-42 was collected from plasma.