Table 5.
Sample size calculations for evaluation of G6PD diagnostic tests for radical cure
| Expected sensitivity | Desired width of CI | Confidence level | Number of disease cases needed |
Sample size |
||
|---|---|---|---|---|---|---|
| Prevalence rate 10% | Prevalence rate 15% | Prevalence rate 20% | ||||
| 0.8 |
0.06 |
0.95 |
715 |
7150 |
4767 |
3575 |
| 0.8 |
0.1 |
0.95 |
264 |
2640 |
1760 |
1320 |
| 0.9 |
0.06 |
0.95 |
417 |
4170 |
2780 |
2085 |
| 0.9 |
0.1 |
0.95 |
158 |
1580 |
1053 |
790 |
| 0.95 |
0.06 |
0.95 |
238 |
2380 |
1587 |
1190 |
| 0.95 |
0.1 |
0.95 |
94 |
940 |
627 |
470 |
| 0.96 |
0.06 |
0.95 |
200 |
2000 |
1333 |
1000 |
| 0.96 |
0.1 |
0.95 |
81 |
810 |
540 |
405 |
| 0.97 |
0.06 |
0.95 |
161 |
1610 |
1073 |
805 |
| 0.97 |
0.1 |
0.95 |
68 |
680 |
453 |
340 |
| 0.98 |
0.06 |
0.95 |
123 |
1230 |
820 |
615 |
| 0.98 |
0.1 |
0.95 |
55 |
550 |
367 |
275 |
| 0.99 |
0.06 |
0.95 |
87 |
870 |
580 |
435 |
| 0.99 | 0.1 | 0.95 | 44 | 440 | 293 | 220 |
CI: confidence interval.