Table 3.
Parameters of the model for delay effects (see Eqs. 9 and 10) estimated for four blood lines. Alternative models are shown for neutrophiles and erythrocytes
Blood count distributions |
Mixing distribution |
μ0 [C]1 |
Scale2 [C]1 |
α y Gy−1 |
kW | λW3 (y) |
Mean (y) |
Std (y) |
|
---|---|---|---|---|---|---|---|---|---|
Lymphocytes | Lognormal | Exponential | 2.26 | 0.35 | −0.73 | 1 | 0.017 | 0.017 | 0.017 |
Neutrophiles | Lognormal | Exponential | 3.74 | 0.36 | −0.68 | 1 | 0.72 | 0.72 | 0.72 |
Platelets | Gamma | Weibull | 245.6 | 15.1 | −1.47 | 1.69 | 1.13 | 1.01 | 0.61 |
Uniform | 245.7 | 15.1 | −1.46 | 2.00 | 1.00 | 0.58 | |||
Erythrocytes | Normal | Weibull | 4.30 | 0.40 | −0.42 | 2.14 | 1.09 | 0.96 | 0.47 |
Uniform | 4.30 | 0.40 | −0.42 | 1.92 | 0.96 | 0.55 |
[L]=[N]=[P]= 109cells/mL and [R]= 1012cells/mL
Scale parameter is blood count distribution specific: σ for normal and gamma distributions and σ̃ for a lognormal distribution
λW for different mixing distributions is defined by Eq. (10).