Table 2.
Change from Baseline to Follow-up (Δ) in Peripheral Blood Mononuclear Leukocyte Production of Interleukin-10 and Tumor Necrosis Factor-α in Response to Lipopolysaccharide (Lipopolysaccharide Stimulated Minus Unstimulated)
| Gestational Age at Delivery (Weeks)
|
P* | |||
|---|---|---|---|---|
| Prior to 35 | 35–36 | 37 or After | ||
| IL-10 | ||||
| Number of paired samples† | 39 | 64 | 189 | |
| Median Δ‡ | −65.2 | 48.9 | 159.3 | .01 |
| Range‡ | −5394.5, 1932.4 | −4020.5, 3916.8 | −3868.6, 16094.4 | |
| Interquartile range‡ | −1217.4, 254.3 | −843.0, 563.1 | −356.2, 925.2 | |
| TNF-α | ||||
| Number of paired samples | 48 | 70 | 201 | |
| Median Δ‡ | 132.1 | −356.0 | 86.9 | .03 |
| Range‡ | −4753.5, 13008.9 | −13491.8, 20640.9 | −10151.3, 14578.7 | |
| Interquartile range‡ | −1218.0, 817.0 | −2307.5, 334.2 | −964.3, 1108.2 | |
IL-10, interleukin-10; TNF-α, tumor necrosis factor-α.
*
Kruskal-Wallis test
†
Paired samples from the same patients at baseline and follow-up.
‡
Data are median, range, and interquartile range in pg/mL by gestational age at delivery.