Table 3.

Change From Baseline to Follow-up (Δ) in Peripheral Blood Mononuclear Leukocyte Production of Interleukin-10 and Tumor Necrosis Factor-α in Response to Lipopolysaccharide (Lipopolysaccharide Stimulated Minus Unstimulated)

	Fish Diet History			Treatment Assignment
	Fewer Than 1 Meal per Week	1 or More Meals per Week	P +	Omega-3	Placebo	P*
IL-10
Number of paired samples†	137	155		167	125
Median Δ +	72.5	120.6	.36	120.6	72.5	.91
Range +	−5394.5, 16094.4	−3100.5, 5833.8		−5394.5, 16094.4	−4020.5, 3916.8
Interquartile range +	−652.4, 651.7	−437.0, 846.3		−542.2, 700.6	−470.3, 836.6
TNF-α
Number of paired samples†	152	167		174	145
Median Δ +	−198.1	95.4	.10	20.9	−3.1	.55
Range +	−13429.3, 20640.9	−13491.8, 14578.7		−13491.8, 14578.7	−10151.3, 20640.9
Interquartile range+	−1673.4, 790.2	−931.8, 1103.2		−1205.5, 1158.8	−1154.1, 762.5

IL-10, interleukin-10; TNF-α, tumor necrosis factor-α.

^*Kruskal-Wallis test

^†Paired samples from the same patients at baseline and follow-up

^‡Data are median, range, and interquartile range in pg/mL by fish diet and treatment assignment