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. Author manuscript; available in PMC: 2014 Mar 10.
Published in final edited form as: Sci Signal. 2013 Sep 10;6(292):10.1126/scisignal.2004324. doi: 10.1126/scisignal.2004324

Fig. 2. Jub is required for Drosophila wing regeneration and for neoplastic tumor growth in wing discs with lgl knock-down.

Fig. 2

A) Distribution of adult wing sizes in rn-Gal4 UAS-egr tubGal80ts (N=78) or rn-Gal4 UAS-egr tubGal80ts jubE1/+ (N=105) flies after larval wing ablation and recovery. B–F) Representative wings of 100% (B), 70% (C), 50% (D), 30% (E) and 10% (F) wild-type size. G) Quantification of the ratios of mean intensity of ex-lacZ expression in posterior to anterior compartments for the indicated genotypes (N=3 discs per genotype). H) Quantification of the ratios of area of the posterior to anterior compartments for the indicated genotypes (N=3 discs per genotype). Error bars indicate standard error, and P values less than 0.05 are shown. I–L) Wing discs stained for ex-lacz (β-gal, magenta) and with the posterior marked by expression of en-Gal4 UAS-GFP (green). The right part of each panel shows the ex-lacZ only stain from the image to the left. Discs are from animals with ex-lacZ, en-Gal4 and UAS-GFP transgenes and I) UAS-lglRNAi, J) UAS-lglRNAi UAS-bskRNAi, K) UAS-lglRNAi UAS-myc:wts, L) UAS-lglRNAi UAS-jubRNAi.