Table 2.
Characteristics of Patients With Fluoroquinolone-Resistant and -Susceptible Staphylococcus aureus Isolatesa
| Baseline Characteristics | Resistant (n=41) | Susceptible (n=159) | P Value |
|---|---|---|---|
| Age, mean (SD), y | 65.5 (25.0) | 52.1 (22.1) | .003 |
| Male | 39.0 | 46.5 | .48 |
| Culture site | |||
| Eyelid | 48.8 | 37.1 | .11 |
| Conjunctiva | 4.9 | 5.0 | |
| Eyelid and conjunctiva | 34.2 | 51.6 | |
| Cornea | 9.8 | 6.3 | |
| Lacrimal sac | 2.4 | 0.00 | |
| Eye | |||
| Right | 36.6 | 29.6 | 0.21 |
| Left | 12.2 | 24.5 | |
| Both | 51.2 | 45.9 | |
| MRSA | 78.1 | 0.00 | <.001 |
| Topical FQ use within 3 mo | 29.3 | 10.7 | .005 |
| Topical FQ use >3 mo ago | 4.9 | 0.6 | .11 |
| Oral FQ | 4.9 | 0.6 | .11 |
| Other topical antibiotic | 43.9 | 27.7 | .06 |
| Other systemic antibiotic | 7.3 | 5.7 | .71 |
| Systemic immunosuppression | 22.0 | 15.7 | .36 |
| Topical immunosuppression | 19.5 | 25.8 | .54 |
| Recent hospitalization | 22.0 | 0.00 | <.001 |
Abbreviations: FQ, fluoroquinolone; MRSA, methicillin-resistant S aureus.
a
Unless otherwise indicated, data are reported as percentage of isolates.