Table 1. Demographic characteristics and their associations with UFs in the Right from the Start (2001-2012) and BioVU (2007-present) cohorts.
| A. RFTS Cohort | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Characteristic | No UFs (n = 552) %/mean(SD) |
UFs (n = 89) %/mean(SD) |
OR | 95 % CI | ||
|
| ||||||
| Lower | Upper | |||||
| Age mean (SD) | 641 | 29.95(4) | 32.65(5) | 1.14 | 1.08 | 1.20 |
| Age Categories | ||||||
| < 25 | 58 | 10 | 2 | 1.00 | Reference | |
| 25-29 | 230 | 38 | 21 | 2.52 | 0.57 | 11.15 |
| 30-34 | 239 | 37 | 42 | 5.12 | 1.20 | 21.94 |
| 35-49 | 114 | 15 | 35 | 10.46 | 2.41 | 45.46 |
| ≥ 50 | 0 | 0 | 0 | - | - | - |
| Body mass index mean (SD) | 634 | 25.36(6) | 26.15(6) | 1.03 | 0.99 | 1.06 |
| Body mass index categories | ||||||
| Underweight (< 20) | 68 | 11 | 8 | 0.74 | 0.32 | 1.74 |
| Normal weight (20-24.9) | 307 | 48 | 46 | 1.00 | Reference | |
| Overweight (25-29.9) | 152 | 24 | 24 | 1.04 | 0.59 | 1.83 |
| Obese (≥ 30) | 114 | 17 | 22 | 1.38 | 0.77 | 2.48 |
| Study site | ||||||
| North Carolina | 195 | 28 | 54 | 2.20 | 1.39 | 3.47 |
| Tennessee | 444 | 72 | 46 | 1.00 | Reference | |
| Texas | 2 | <1 | 0 | - | - | - |
| UF Type1 | ||||||
| Any Submucous | 20 | - | 17 | - | - | - |
| Any Intramural | 58 | - | 49 | - | - | - |
| Any Subserous | 41 | - | 34 | - | - | - |
| UF number | ||||||
| One | 63 | - | 71 | - | - | - |
| Two or more | 26 | - | 29 | - | - | - |
| Total UF volume | ||||||
| Top quartile (0.003-0.7) | 25 | - | 0.33(0.23) | - | - | - |
| 2nd quartile (0.7- 3.6) | 21 | - | 1.47(0.71) | - | - | - |
| 3rd quartile (3.6-13.3) | 26 | - | 7.33(2.66) | - | - | - |
| 4th quartile (16.6-179.1) | 17 | - | 65.38(48.64) | - | - | - |
|
| ||||||
| B. | ||||||
|
| ||||||
| Characteristic | n |
No UFs (n = 997) %/mean(SD) |
UFs (n = 367) %/mean(SD) |
OR | 95% CI | |
|
| ||||||
| Lower | Upper | |||||
|
| ||||||
| Age mean (SD) | 1,364 | 57.45(18) | 53.58(11) | 0.99 | 0.98 | 0.99 |
| Age Categories | ||||||
| < 25 | 15 | 1 | <1 | 1.00 | Reference | |
| 25-29 | 54 | 5 | <1 | 0.26 | 0.02 | 4.49 |
| 30-34 | 84 | 8 | 3 | 1.68 | 0.20 | 14.33 |
| 35-49 | 334 | 21 | 37 | 9.26 | 1.20 | 71.28 |
| 50-64 | 433 | 28 | 43 | 7.96 | 1.04 | 61.14 |
| ≥ 65 | 411 | 36 | 17 | 2.39 | 0.31 | 18.54 |
| Body mass index mean (SD) | 1,285 | 27.80(8) | 28.03(7) | 1.00 | 0.99 | 1.02 |
| Body mass index categories | ||||||
| Underweight (< 20) | 82 | 7 | 4 | 0.54 | 0.29 | 0.98 |
| Normal weight (20-24.9) | 374 | 29 | 31 | 1.00 | Reference | |
| Overweight (25-29.9) | 379 | 29 | 31 | 0.98 | 0.72 | 1.34 |
| Obese (≥ 30) | 450 | 35 | 34 | 0.90 | 0.67 | 1.22 |
| UF Type1 | ||||||
| Any submucous | 150 | - | 31 | - | - | - |
| Any intramural | 212 | - | 44 | - | - | - |
| Any subserous | 115 | - | 24 | - | - | - |
n = number, OR = odds ratio from logistic regression, CI = confidence interval, mean(SD) = mean(standard deviation)
1
Fibroid type do not sum to total number of fibroids because subjects may have had more than one fibroid type observed