Table 1.

Cross-sectional studies of cognition across menopause transition stages

Study	Demographics			Stage					Cognitive Domain
	N	Mean Ed	Mean Age	Pre	Early Peri	Late Peri	Peri	Post	Working Memory	Executive Functions			Verbal Memory
										PS	PVF	SVF	Imm	Delay
Luetters et al. 2007a [41]	1567	14.5b	49.8c	X	X	X		X	ns	ns			ns	ns
Herlitz et al. 2007d [42]	242	13.5 c	49.4 c	X			X	X			ns
Berent-Spillson, et al. 2012e[40]	67	14	52.0	X			X	X			↓	ns	ns	ns
Weber et al. 2013f[43]	117	16	48.7	X	X	X		X	↓	ns	ns	ns	↓	↓

↓ indicates decreased performance in postmenopause relative to premenopause, ns indicates no significant difference. Ed-years of education, PS-processing speed, SVF-semantic verbal fluency, PVF-phonemic verbal fluency, Imm-Immediate memory, Delay-delayed memory

^aadjusted for site, age, race, education, BMI, self-reported poor health, vasomotor symptoms, poor sleep, somatic symptoms, and dysphoric mood symptoms

^bEducation was reported as post-college, college, some college, HS, and < HS. We assigned respective years of 18, 16, 13, 12, and 9, and derived a pooled mean.

^cpooled mean

^dadjusted for age and education

^eadjusted for age

^fadjusted for age, education, vasomotor symptoms , sleep disturbance, depressive symptoms, anxiety symptoms, estradiol, and follicle-stimulating hormone