Table 1.

Psychometric information on cognitive measures^a

Cognitive Measure	Function Assessed	Items	Baseline Evaluation		Last Evaluation		Annual Change*
			Evaluation	SD	Mean	SD	Change*	SE	p
Logical Memory Ia	Episodic memory	25	11.8	3.7	8.6	5.7	−0.078	0.013	<0.001
Logical Memory IIa	Episodic memory	25	10.0	4.0	7.8	5.5	−0.061	0.012	<0.001
Immediate story recall	Episodic memory	12	9.8	1.8	7.2	3.5	−0.123	0.015	<0.001
Delayed story recall	Episodic memory	12	9.2	2.2	6.5	3.8	−0.108	0.015	<0.001
Word List Memory	Episodic memory	30	17.5	4.0	14.0	7.0	−0.091	0.016	<0.001
Word List Recall	Episodic memory	10	5.4	2.1	3.8	3.0	−0.070	0.013	<0.001
Word List Recognition	Episodic memory	10	9.6	1.2	8.1	3.1	−0.110	0.023	<0.001
Vocabulary test	Semantic memory	15	10.6	3.3	8.7	4.5	−0.053	0.011	<0.001
Reading test	Semantic memory	20	18.2	2.4	17.0	4.0	−0.036	0.015	0.013
Verbal Fluency	Semantic memory	na	33.5	8.6	21.1	11.9	−0.127	0.012	<0.001
Boston Naming Test	Semantic memory	20	18.0	1.9	15.7	4.5	−0.101	0.016	<0.001
Digit Span Forward	Working memory	12	8.4	2.0	7.1	2.8	−0.046	0.013	<0.001
Digit Span Backward	Working memory	12	6.1	1.9	4.5	2.6	−0.066	0.012	<0.001
Digit ordering	Working memory	16	6.8	2.7	5.5	2.5	−0.051	0.009	<0.001
Alpha span	Working memory	14	4.8	1.6	2.8	1.9	−0.099	0.011	<0.001
Symbol Digit Modalities Test	Perceptual speed	110	38.4	10.0	23.6	14.8	−0.125	0.011	<0.001
Number Comparison	Perceptual speed	48	24.2	6.5	16.3	8.9	−0.106	0.012	<0.001
Line Orientation	Visuospatial ability	15	9.7	3.2	7.7	3.8	−0.066	0.010	<0.001
Standard Progressive Matrices	Visuospatial ability	17	9.8	3.2	7.8	3.4	−0.052	0.009	<0.001
Mini-Mental State Examination	Global cognition	30	28.3	1.6	21.0	9.4	−0.215	0.030	<0.001

^aFrom 20 separate mixed-effects models adjusted for age at death.