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. Author manuscript; available in PMC: 2014 Jun 1.

Published in final edited form as: Kidney Int. 2013 Jun 5;84(6):1166–1175. doi: 10.1038/ki.2013.209

Table 1.

POP Activity and Ac-SDKP Concentration

	Day 5 UUO				Day 14 UUO
	WT		PAI-1−/−		WT		PAI-1−/−
Treatment	POP activity	Ac-SDKP	POP activity	Ac-SDKP	POP activity	Ac-SDKP	POP activity	Ac-SDKP
	pmol/ min^* mg tissue	pmol/ mg tissue	pmol min^* mg tissue	pmol/ mg tissue	pmol/ min^* mg tissue	pmol/ mg tissue	pmol/ min^* mg tissue	pmol/ mg tissue
Control	27.60±2.26	1.40±0.19	27.38±1.00	1.31±0.04	13.78±3.18	1.07±0.15	18.31±0.97	1.11±0.13
POPi	2.06±0.26^*	0.66±0.08^*	2.17±0.16^*	0.61±0.10^*	ND	ND	ND	ND
Tβ4+POPi	5.73±1.59^*	0.86±0.09^*	7.99±0.80^*	1.00±0.15^*	4.04±0.80^*	0.54±0.13^*	7.48±1.52^*	0.47±0.05^*
Tβ4	21.18± 1.61	1.09±0.12	23.29±1.58	1.26±0.32	12.24±1.51	1.58±0.17^*	12.56±4.77	1.22±0.30
Ac-SDKP	31.88±1.18	2.41±0.08^*	29.03±1.25	2.61±0.16^*	16.68±2.40	2.11±0.23^*	12.04±2.87	2.49±0.20^*

Abbreviations: POPi, POP inhibitor; Tβ4+POPi, thymosin β4 plus POP inhibitor; Tβ4, thymosin β4; ND, not done.

Data are shown as mean ± SEM

^*

p<0.05 vs. its control, n=5–8 in each group.