β-catenin binding to known Wnt target genes related to differentiation (Cdx2, A), and pluripotency (Nanog, B). Endogenous association of β-catenin is also displayed in the absence of CHIR stimulation (CHIR-). Tcf3, Nanog, Oct4, Sox2 and histone modification profiles displayed here are from published datasets (see Results). A zoom in on highlighted regions with motif annotation is displayed to the right side.