Table 2.
Clinicopathological and molecular characteristics of SHH medulloblastoma according to TERT mutational status
| Characteristic | TERT MUT | TERT WT | p value |
|---|---|---|---|
| Age (years) | |||
| Median | 25.00 | 3.00 | <0.0001 # |
| Range | 0.66–49.00 | 0.24–52.00 | |
| NA | 1 | 0 | |
| Gender | |||
| Male | 46 | 80 | 0.77Φ |
| Female | 31 | 48 | |
| NA | 3 | 5 | |
| Histology | |||
| MBEN | 3 | 4 | 0.04 χ |
| Desmoplastic | 10 | 44 | |
| Classic | 34 | 47 | |
| LC/A | 10 | 16 | |
| NA | 23 | 22 | |
| M-stage | |||
| M0 | 46 | 87 | 0.84Φ |
| M1-3 | 10 | 22 | |
| NA | 24 | 24 | |
| TP53 status | |||
| MUT | 4 | 8 | 1Φ |
| WT | 38 | 71 | |
| NA | 38 | 54 | |
F female, LC/A large cell/anaplastic, M male, MB medulloblastoma, MBEN medulloblastoma with extensive nodularity, NA not available (data were excluded from statistical comparison)
Bold values indicate p < 0.05
#Mann–Whitney U test
ΦFisher’s exact test
χChi-square test